FAQs

Participating in a research study is different from receiving standard medical care, which is intended to treat a condition or disease. The purpose of a research study is to collect information about an investigational treatment.

If you participate in a research study, you will be evaluated by study doctors and nurses on a regular basis during your participation.

Using the information collected in research studies, study doctors and regulatory health agencies can determine if an investigational treatment could one day be made available to the public.

By participating in the EXPLORE research study, you could help advance research for difficult-to-treat RA.

The purpose of the EXPLORE research study is to see if IMVT-1402 is safe and helps people with difficult-to-treat RA.

Around 120 people will take part in this research study.

Please keep these responsibilities in mind during your study participation:

• Follow all instructions from the study doctor and staff
• Answer questions about your health to the best of your knowledge
• Come to all scheduled study clinic visits
• Complete all research study questionnaires/rating scales
• Complete your dosing diary every time you receive or administer injections of the study treatment
• Tell the study doctor or staff about any changes in your health, medications, or the way you feel
• Tell the study doctor or staff about any new medications or therapies you are taking
• Continue making regular visits to your family/personal doctor or any other specialists
• Follow the birth control requirements described in the informed consent form (ICF)
• Tell the study doctor or staff if you or your partner becomes pregnant during the study
• Do not participate in any other research studies while you are in this study
• Tell the study doctor or staff about any medical care you receive outside this study
• If you visit an emergency room or receive any other medical care outside this study, please tell the healthcare professionals treating you that you are participating in this study. This information will help them better care for you.

While you could receive some benefit from participating in this study, that is not guaranteed. It is also possible your RA may get worse. However, your study participation may help people with difficult-to-treat RA in the future.

Prior to you joining the study, the study doctor/staff will talk with you about the potential risks, benefits, and side effects related to this study, as well as answer any questions you may have. Throughout your study participation, your health will be closely monitored for any signs of side effects.